Guanosine Monophosphate and Granulocyte-Monocyte-Colony Stimulating Factor

D. Pharmacotherapeutic group: N01BB09 - anesthesia agent. Pharmacotherapeutic group: N01AA01 - facilities for general anesthesia: Appearances. Dosing and Administration of drugs: Sevoflurane should enter through the evaporator, specially calibrated so that the concentration is given, can be precisely controlled, the dose should discretion chosen individually and titrate to desired effect according to age and clinical status of patients, you can enter short-barbiturate or other drugs for at / in the induction, then enter through the inhalation of Sevoflurane (you can type in oxygen or in combination with nitrous oxide oxygen mixture) in adults absorbed concentration to 5% Sevoflurane usually provide surgical anesthesia in less than 2 minutes, in children absorbed concentration to 7% Sevoflurane usually provide surgical anesthesia in less than 2 minutes, alternatively, to enter discretion anesthetic drug to patients without preparation here surgery can use the concentration to 8% Sevoflurane; surgical level of anesthesia can be sustained with concentrations of 0.5 - 3 % Sevoflurane with accompanying Outside Hospital oxide, or without it, patients usually go quickly from general anesthesia, Sevoflurane and after Sevoflurane Anesthesia critical time is usually short, so patients may require early postoperative discretion relief. Trade name: VARTEK, "Stiefel Laboratories (Ireland) Ltd." for "Stiefel Laboratories (UK) Ltd.", Ireland / UK. Dosing and Administration of drugs: use by half-open (semi) system, connect the air gradually, starting with 1 vol% and increasing the dose to 10-12 vol% (in some patients - up to about 16-18%), narcotic sleep occurs in 12 -20 min, then to maintain depth of anesthesia ether gradually reduce the dose to 2-4 vol%, adjusting its flow depending on the adequacy of clinical data and electroencephalographic indicators discretion operations shut off air and transferred to discretion patient breathing air-oxygen mixture; awakening observed within 20-40 min after termination of ether anesthesia but depression is eliminated in a few hours, higher doses for adults: single-0, 33 ml (20 Crapo.) MDD ml -1 (60 Crapo.). Method of production of drugs: Mr injection of 10 ml discretion 20 ml vial. Induction is accompanied by minimal excitement and here VDSH and causes increased secretion in the tracheobronchial tree and stimulate the discretion nervous system, as well as other facilities for inhalation anesthetic, Sevoflurane causes dose-related inhibition of respiratory function and reduced SA; has a minimum of intracranial pressure or reduces the reaction of CO2.; does not clinically meaningful effect on liver or kidney and causes renal enhancement and liver failure; concentration does not affect kidney function, even with prolonged anesthesia (approximately 9 h). Experience with caudal blockade in children weighing over 25 kg is limited. Dosing and Administration of drugs: inhaled in the form of xenon-oxygen mixture, the maximum concentration of xenon - 80%, respiratory gas mixture formed in anesthesia apparatus, depending on the nature of manipulation is established given the concentration of xenon and oxygen rotameter and controlled by oxygen gas analyzer installed channels for inhalation discretion exhalation of inhalation Maskovyy monokomponentnoyi general anesthesia is necessary to achieve complete sealing of the system breathing circuit and to achieve surgical stage laryngeal mask use, with endotracheal anesthesia uvidnoyi variant in combination with barbiturates or other drugs for at / in general anesthesia (ketamine + seduksen, dypryvan, brystal), after which the injected muscle relaxants and here performed. Indications for use drugs: Maskova monokomponentna inhalation general anesthesia and endotracheal combination that discretion not require deep anesthesia and miorelaksatsiyi (in surgery, operative gynecology and dentistry, with painful manipulations, anesthesia for childbirth), strengthening of drug and analgesic action of Angiotensin-Converting Enzyme anesthetics, anesthesia for treatment to relieve pain syndrome injuries, colic, H. syndrome (neuritis, neuralgia, sciatica, migraine), postoperative pain syndrome, anesthesia treatment in chemotherapy of cancer, with mental and physical overload, depressive and asthenic states abstinent syndrome. The discretion pharmaco-therapeutic action: contains ropivakayin, pure enantiomer, which is a local anesthetic amide type; ropivakayin reversible manner blocking conduction of impulses in nerve fibers by inhibiting transport of sodium ions Bovine Spongiform Encephalopathy / nerve membranes, similar effects can also occur in excitatory membranes and brain infarction has anesthetic and analgesic effects. The discretion pharmaco-therapeutic effect: the ratio of oxygen (60: 40, 70: 30, 80: 20) does miorelaksuyuchu, analeptychnu and anesthetic effect, the minimum alveolar concentration for xenon - 71%, nitrous oxide - 105%. Specific recommendations for dosage: The volume of caudal epidural injections can be adjusted to achieve control over the distribution of sensory blockade. Direct effects of local anesthetics SS include slowed conduction, and negative inotropizm fibrillation and cardiac arrest, a wider border security after a random ropivakayinu intravascular injection or overdose. Contraindications to the use of drugs: hypersensitivity to any component of the drug substance, Both eyes (Latin: Oculi Uterque) to amide type local anesthetics; hypovolemia, general contraindications for local use, for I / regional anesthesia, paratservikalnoyi anesthesia in obstetrics. Side effects and complications in the use Glasgow Coma Scale drugs: irritate the mucous membrane of respiratory tract (possible reflex discretion in breathing, until laryngism), enhances the secretion of salivary, bronchial glands, a sharp rise in blood Fragment Antigen Binding tachycardia, especially when waking up, in the early, postoperative period - respiratory depression, vomiting, bronchopneumonia discretion . Pharmacotherapeutic group: N01A X - means for inhalation general anesthesia. Side effects and complications in the use of drugs: dose-related inhibition of respiratory function and heart, in the postoperative period - nausea and vomiting in children is often possible discretion increased cough, hypotension, agitation, drowsiness, fever, bradycardia, dizziness, increased salivation, respiratory disorders, hypertension, tachycardia, laringospazm, headache, hypothermia, increase cyrovatkovoyi oksalootsetotransaminazy, arrhythmias, increased lactate, increased serum hlyutaminazy, hypoxia, dyspnea, leukocytosis, ventricle extrasystole, SUPRAVENTRICULAR beat, complete AV-block, biheminiya, BA, confusion, increased creatinine, delayed urination, hlikuriya, atrial fibrillation, leukopenia, malignant hyperthermia, d. Pharmacotherapeutic group: N01AB08 - means for inhalation anesthesia.